Validating Organ-on-Chip Models Across Platforms to Enhance Safety Predictions & Translational Accuracy

• Establishing project-specific validation criteria for organ-on-chip systems to assess translatability against animal studies and clinical outcomes
• Implementing multi-organ approaches including blood, liver, and skin-on-chip models to address diverse safety and efficacy questions
• Standardizing assay protocols across cell therapy and small molecule platforms to ensure reproducible safety hazard predictions

Speakers:

Elham Malekzadeh

Senior Scientist

Takeda Pharmaceutical