Malini Iyer
Associate Director - Oncology Safety Sciences AstraZeneca
Seminars
Wednesday 29th April 2026
Implementing Strategic In Vitro Model Validation to Accelerate Safe ADC Development & Clinical Translation
2:00 pm
- Establishing model selection criteria for safety assessment to identify appropriate organ systems and predict ADC toxicity endpoints early
- Implementing 3D to 2D validation strategies to streamline cell-based assays while maintaining predictive accuracy for safety screening
- Integrating mathematical modeling with in vitro systems to enhance clinical risk prediction and accelerate safer ADC development programs
