Explore the Agenda
8:00 am Registration & Morning Coffee
8:55 am Chair’s Opening Remarks
Advancing Automation & Standardization in Complex Model Systems to Enable Scalable High-Throughput Applications
9:00 am Optimizing Robotic Workflow Protocols to Enhance Scalability & Speed Up Organoid Development
- Designing automated robotic systems to streamline workflow protocols and reduce manual variability in organoid production
- Optimizing organoid-specific workflows to accelerate scalability and ensure readiness for diverse organotypic models
- Implementing tailored automation strategies to shorten tissue maturation timelines and improve reproducibility across multiple organoid types
9:30 am Achieving Robust QC Standards in 3D Vascular Models to Enable Confident Preclinical Implementation
- Establishing reproducible quality control protocols for 96-well 3D vascular models to ensure device readiness across multiple plates
- Validating barrier integrity measurements in outsourced 3D vascular systems to accelerate compound screening with minimal internal development
- Implementing scalable pre-clinical screening workflows using ready-to-use 3D models to enable rapid adoption for future therapeutic programs
10:00 am Morning Break & Announcement of the Poster Winner
The winning poster will be selected by our advisory board during the meeting. The winner will receive an engraved trophy and certificate, and have their poster showcased on our website as a downloadable file (subject to T&Cs).
Applying Biostatistical & Experimental Design Strategies to Ensure Validity, Reproducibility, & Scalability in CIVMs
10:30 am Roundtable Discussion: Integrating Biostatistical Frameworks & Experimental Design to Establish Reproducibility Standards & Enable Regulatory Confidence
Join an interactive session where the audience is divided into small groups to explore key challenges in 3D tissue modeling. After the discussions, each group will share insights with the room so everyone can learn from their peers.
- Defining statistical validation requirements including sample sizes and confidence intervals to ensure robust physiological relevance claims
- Standardizing experimental protocols and quality control measures to minimize variability and meet regulatory expectations for model qualification
- Applying data science tools and predictive modeling to guide scalable development decisions and translate complex datasets into actionable insights
Moderator:
Mastering Reproducibility Strategies to Control Variability in Complex In Vitro Models
11:30 am Controlling Environmental Variability to Improve Predictability in Muscleon- a-Chip Models for Neuromuscular Research
- Standardizing microenvironmental conditions to ensure reproducibility and reduce variability in neuromuscular junction and muscle-on-chip systems
- Implementing controlled culture parameters to maintain physiological relevance and enhance translational accuracy for efficacy studies
- Optimizing environmental monitoring strategies to minimize external influences and deliver consistent pharmacology readouts across experiments
12:00 pm Lunch Break & Networking
1:00 pm Mastering Cell Qualification & Reproducibility in MPS Platforms to Achieve Translational Accuracy & Biological Relevance
- Establishing comprehensive cell qualification protocols beyond device engineering to ensure true biological function and physiological relevance in MPS systems
- Defining disease-specific measurement metrics and functional endpoints to validate reproducibility and support translational predictions across organ platforms
- Implementing collaborative validation frameworks across liver and multiple organ systems to standardize reproducibility criteria and enhance predictive modeling
Enabling 3D Tissue Models High Throughput to Accelerate Early Discovery & Streamline Screening Processes
1:30 pm Roundtable Discussion: Implementing Automation Strategies in Complex Model Systems to Achieve High-Throughput Screening Capabilities & Scalability
Join an interactive session where the audience is divided into small groups to explore key challenges in 3D tissue modeling. After the discussions, each group will share insights with the room so everyone can learn from their peers.
- Transitioning manual protocols to automated workflows to enable high-throughput applications while maintaining model integrity and reproducibility
- Addressing technical challenges in scaling complex model systems to achieve throughput levels required for large screening campaigns
- Integrating robotic platforms and liquid handling systems to streamline model setup and accelerate data generation efficiency
Moderator:
2:30 pm Afternoon Break & Refreshments
Leveraging Complex 3D Models for Target Identification & Safety to Overcome Animal Model Translational Limitations
3:00 pm Advancing Regulatory Pathways for Complex In Vitro Models to Enhance Predictive Toxicity Assessments
- Establishing evidentiary considerations for model validation and qualification to align with global health authority requirements and standards
- Identifying context of use and unmet needs for complex in vitro models to address near-term regulatory applications
- Integrating models throughout pharmaceutical pipelines from high-throughput screening to IND applications to accelerate development timelines
3:30 pm Advancing Target Identification & Validation Using Complex 3D Models to Overcome Animal Model Limitations
- Establishing 3D model systems for target translatability to address gaps where animal models lack relevant therapeutic targets
- Contrasting 2D versus 3D model capabilities to demonstrate complex system advantages and secure essential leadership investment support
- Implementing rapid model qualification workflows in fast-paced biopharma environments to accelerate target validation and therapeutic development timelines
4:00 pm Chair’s Closing Remarks
4:05 pm End of Conference Day Two
No day selected